CT-Guided Oxygen-Ozone Intradiscal Injection Therapy for Thoracolumbar Intervertebral Disc Herniations (Hansen Type II) in Dogs

Abstract

Objective: To study the treatment of thoracolumbar herniated intervertebral discs (IVD) using Oxygen-Ozone (O₂-O₃) intradiscal injection. 

Animals: 3 client-owned dogs with 13 herniated intervertebral discs

Procedure: These intervertebral discs were treated using 0.5 ml percutaneous injection of O₂-O₃ gas mixture, with an O₃ intradiscal concentration of 32 µg/µl under CT guidance, following MRI diagnosis. Five weeks after injection, a second MRI was performed, and six indices (introduced in the paper) were evaluated in all treated IVDs. 

Results: All indices were improved after the treatment. In addition, three were statistically significant at P<0.5. All 3 dogs returned to their normal life after this study.

Conclusion: Intradiscal O₂-O₃ injection reduces the size of the herniated disc via disc shrinkage and decreasing the pressure of herniated part on the spinal cord.